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MS is a chronic inflammatory disease of the CNS that leads to demyelination and neurodegeneration.
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Mullis and co-workers in 1985 revolutionized molecular biology and molecular medicine.
Although the cause of MS is still unknown, it is widely accepted that the acquired immune response plays a key role in disease onset and progression (2, 3).
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Discovery of Differentially Expressed Genes Associated
Supplemental material Supplemental Methods Generation of mice heterozygous for the floxed HMGCR allele A conditional targeting vector of a replacement type was.